Open Sim Lab
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A time nobody can supply

Educational use only. Not clinically reviewed

76-year-old woman for calm timeline recording, uncertainty preservation, activation, and handoff practice. About 7 simulated minutes.

What you will practise

  • Record last known well as a bound.
  • Keep an uncertain account uncertain.
  • Activate on the deficit, not the clock.
  • State what the unknown does and does not change.
  • Review the boundaries and their certainty.
  • Hand over the empty field as empty.

Review and sources

Not clinically reviewed. No clinician has signed this scenario.

  • Thomalla G, Simonsen CZ, Boutitie F, et al. MRI-guided thrombolysis for stroke with unknown time of onset (WAKE-UP). N Engl J Med. 2018;379(7):611-622. doi:10.1056/NEJMoa1804355. Randomised trial in 503 of a planned 800 patients with stroke of unknown onset, stopped when funding ended; favourable outcome 53.3% versus 41.8%, adjusted odds ratio 1.61 (95% CI 1.09-2.36), P=0.02; death 4.1% versus 1.2% (P=0.07) and parenchymal haematoma 4.0% versus 0.4% (adjusted OR 10.46, 95% CI 1.32-82.77, P=0.03). Eligibility rested on imaging as a surrogate for lesion age rather than on a remembered time of onset, and the trial was never powered to measure harm.
  • Difonzo M. Performance of the Afferent Limb of Rapid Response Systems in Managing Deteriorating Patients: A Systematic Review. Crit Care Res Pract. 2019;2019:6902420. At least one vital sign was missing in 77% of patients with adverse events, supporting the general finding that gaps in observation precede unrecognised deterioration.

Every scenario in this module

Open Sim Lab is an educational simulator, not for clinical use. It is not a clinical decision-support tool, not a dosing calculator, and is not validated for any decision affecting a real patient.