Severe acidemia
Educational use only. Not clinically reviewed61-year-old man for Acidemia stabilization and cause review. About 8 simulated minutes.
What you will practise
- Recognize severe mixed acidemia with cardiovascular, respiratory, electrolyte, and kidney risk.
- Confirm the gas and distinguish metabolic acid accumulation from inadequate respiratory compensation.
- Restore safe ventilatory compensation while avoiding normalization-by-force.
- Activate cause-directed shock care and individualized buffer and kidney-support planning.
- Reassess gas, perfusion, ventilation, potassium, kidney, and cause trajectories.
Review and sources
Not clinically reviewed. No clinician has signed this scenario.
- Society of Critical Care Medicine and European Society of Intensive Care Medicine. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026. Intensive Care Med. 2026.
- Jung B, Martinez M, Claessens YE, et al. Diagnosis and management of metabolic acidosis: guidelines from a French expert panel. Ann Intensive Care. 2019;9:92.
- Jung B, Jabaudon M, De Jong A, et al. Sodium Bicarbonate for Severe Metabolic Acidemia and Acute Kidney Injury: The BICARICU-2 Randomized Clinical Trial. JAMA. 2025;334:2000-2010.
- Kidney Disease: Improving Global Outcomes. KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney Int Suppl. 2012;2:1-138.
Open Sim Lab is an educational simulator, not for clinical use. It is not a clinical decision-support tool, not a dosing calculator, and is not validated for any decision affecting a real patient.