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Opioid-induced ventilatory impairment

Educational use only. Not clinically reviewed

68-year-old man for Total knee arthroplasty. About 7 simulated minutes.

What you will practise

  • Recognize advancing sedation and depressed ventilation before oxygen saturation becomes the only signal.
  • Keep the airway patent and support ventilation while definitive reversal is prepared.
  • Hold further opioid instead of chasing a pain score during advancing sedation.
  • Record patient-specific naloxone titration intent without treating one reversal as the end of monitoring.
  • Reassess respiratory rate, tidal volume, carbon dioxide, and oxygenation together.

Review and sources

Not clinically reviewed. No clinician has signed this scenario.

  • Levy N, et al. An international multidisciplinary consensus statement on the prevention of opioid-related harm in adult surgical patients. Anaesthesia. 2021;76:520-536. PMID 33027841.
  • Jansen SC, Dahan A. Opioid-induced respiratory depression. BJA Education. 2024;24:100-106. PMID 38375496.

Every scenario in this module

Open Sim Lab is an educational simulator, not for clinical use. It is not a clinical decision-support tool, not a dosing calculator, and is not validated for any decision affecting a real patient.